Good Day for Horses and Livestock

[Uncle Rico]

https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2789362?guestAccessKey=58760460-df0f-4790-9257-8f3682dca39b&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=021822

Tough day for Buffons

[MUDPT]

Just came here to post this.

[Pakuni]

But Joe Rogan ...

[jesmu84]

But Joe Rogan ...

But rocket...

[Jockey]

From the study:

"In this open-label randomized clinical trial of high-risk patients with COVID-19 in Malaysia, a 5-day course of oral ivermectin administered during the first week of illness did not reduce the risk of developing severe disease compared with standard of care alone."


Duh..., you need to use it for more than 5 days

[pacearrow02]

From the study:

"In this open-label randomized clinical trial of high-risk patients with COVID-19 in Malaysia, a 5-day course of oral ivermectin administered during the first week of illness did not reduce the risk of developing severe disease compared with standard of care alone."


Duh..., you need to use it for more than 5 days

Also from the study

Results  Among 490 patients included in the primary analysis (mean [SD] age, 62.5 [8.7] years; 267 women [54.5%]), 52 of 241 patients (21.6%) in the ivermectin group and 43 of 249 patients (17.3%) in the control group progressed to severe disease (relative risk [RR], 1.25; 95% CI, 0.87-1.80; P = .25). For all prespecified secondary outcomes, there were no significant differences between groups. Mechanical ventilation occurred in 4 (1.7%) vs 10 (4.0%) (RR, 0.41; 95% CI, 0.13-1.30; P = .17), intensive care unit admission in 6 (2.4%) vs 8 (3.2%) (RR, 0.78; 95% CI, 0.27-2.20; P = .79), and 28-day in-hospital death in 3 (1.2%) vs 10 (4.0%) (RR, 0.31; 95% CI, 0.09-1.11; P = .09). The most common adverse event reported was diarrhea (14 [5.8%] in the ivermectin group and 4 [1.6%] in the control group).


So 60% less mechanical ventilation in ivermectin group, 70% reduction in death, and 33% reduction in ICU admission. 

Or am I interpreting that wrong?

[MUDPT]

Also from the study

Results  Among 490 patients included in the primary analysis (mean [SD] age, 62.5 [8.7] years; 267 women [54.5%]), 52 of 241 patients (21.6%) in the ivermectin group and 43 of 249 patients (17.3%) in the control group progressed to severe disease (relative risk [RR], 1.25; 95% CI, 0.87-1.80; P = .25). For all prespecified secondary outcomes, there were no significant differences between groups. Mechanical ventilation occurred in 4 (1.7%) vs 10 (4.0%) (RR, 0.41; 95% CI, 0.13-1.30; P = .17), intensive care unit admission in 6 (2.4%) vs 8 (3.2%) (RR, 0.78; 95% CI, 0.27-2.20; P = .79), and 28-day in-hospital death in 3 (1.2%) vs 10 (4.0%) (RR, 0.31; 95% CI, 0.09-1.11; P = .09). The most common adverse event reported was diarrhea (14 [5.8%] in the ivermectin group and 4 [1.6%] in the control group).


So 60% less mechanical ventilation in ivermectin group, 70% reduction in death, and 33% reduction in ICU admission. 

Or am I interpreting that wrong?

[TSmith34, Inc.]

But rocket...

Won't deter him in the least. He lives in a post-fact world.

[Uncle Rico]

Also from the study

Results  Among 490 patients included in the primary analysis (mean [SD] age, 62.5 [8.7] years; 267 women [54.5%]), 52 of 241 patients (21.6%) in the ivermectin group and 43 of 249 patients (17.3%) in the control group progressed to severe disease (relative risk [RR], 1.25; 95% CI, 0.87-1.80; P = .25). For all prespecified secondary outcomes, there were no significant differences between groups. Mechanical ventilation occurred in 4 (1.7%) vs 10 (4.0%) (RR, 0.41; 95% CI, 0.13-1.30; P = .17), intensive care unit admission in 6 (2.4%) vs 8 (3.2%) (RR, 0.78; 95% CI, 0.27-2.20; P = .79), and 28-day in-hospital death in 3 (1.2%) vs 10 (4.0%) (RR, 0.31; 95% CI, 0.09-1.11; P = .09). The most common adverse event reported was diarrhea (14 [5.8%] in the ivermectin group and 4 [1.6%] in the control group).


So 60% less mechanical ventilation in ivermectin group, 70% reduction in death, and 33% reduction in ICU admission. 

Or am I interpreting that wrong?

You're wrong again.  Stick to Connect 4 with the elderly

[pacearrow02]

Sure, but the data below is also right there to read for yourself.  What is the definition of significant?  Was the data size too small or does it have to be a certain % or CI to be considered significant?

Sincere questions cause if someone told me there was a study published in JAMA with secondary findings that a medication could lessen your chances of being out on a vent by 70% i sure as hell would find that significant.

[tower912]

This must be some of the big news we were promised.

Snake.


Oil.

[rocky_warrior]

Sincere questions cause if someone told me there was a study published in JAMA with secondary findings that a medication could lessen your chances of being out on a vent by 70% i sure as hell would find that significant.

Well, by your logic, it appears by taking ivermectin makes you 20% more likely to progress to severe disease!  If you like that sales pitch, take all your want!

52 of 241 patients (21.6%) in the ivermectin group and 43 of 249 patients (17.3%) in the control group progressed to severe disease

[tower912]

Well, by your logic, it appears by taking ivermectin makes you 20% more likely to progress to severe disease!  If you like that sales pitch, take all your want!

Please.

[TSmith34, Inc.]

Sure, but the data below is also right there to read for yourself.  What is the definition of significant?  Was the data size too small or does it have to be a certain % or CI to be considered significant?

Sincere questions cause if someone told me there was a study published in JAMA with secondary findings that a medication could lessen your chances of being out on a vent by 70% i sure as hell would find that significant.

[MU82]

Great. The Deep State has infiltrated Malaysian studies of the greatest Covid cure known to man (and horses)!

What they're not telling us is that Dominion rigged this study.

[pacearrow02]

All very serious answers.  You guys are doing great!

[ATL MU Warrior]

When I was a kid, I had a horse. His name was El Bandito. He was smarter than Pace and RoQQet combined.

[Pakuni]

All very serious answers.  You guys are doing great!

Troll big angry people no take troll seriously.

[pacearrow02]

Troll big angry people no take troll seriously.

Remember when you said I was wrong in saying the FDA delayed their decision regarding the Pfizer vaccine for young kids because it wasnt working?  Shocking, you were spreading misinformation.....again.

https://www.google.com/amp/s/www.wsj.com/amp/articles/lower-omicron-efficacy-delayed-fda-review-on-pfizer-shot-in-kids-under-5-11645192800

[Pakuni]

Remember when you said I was wrong in saying the FDA delayed their decision regarding the Pfizer vaccine for young kids because it wasnt working?  Shocking, you were spreading misinformation.....again.

https://www.google.com/amp/s/www.wsj.com/amp/articles/lower-omicron-efficacy-delayed-fda-review-on-pfizer-shot-in-kids-under-5-11645192800

You were wrong and remain wrong.
Maybe for once in your life you should read beyond the headline.

[MUDPT]

Sure, but the data below is also right there to read for yourself.  What is the definition of significant?  Was the data size too small or does it have to be a certain % or CI to be considered significant?

Sincere questions cause if someone told me there was a study published in JAMA with secondary findings that a medication could lessen your chances of being out on a vent by 70% i sure as hell would find that significant.

Easy answer is that it's not 10 vs. 4, it's 14 in 490.  There isn't enough clinical difference in the groups to say it's better or worse.

[rocky_warrior]

Easy answer is that it's not 10 vs. 4, it's 14 in 490.  There isn't enough clinical difference in the groups to say it's better or worse.

490 too big for pace. 14 ok.

[pacearrow02]

Easy answer is that it's not 10 vs. 4, it's 14 in 490.  There isn't enough clinical difference in the groups to say it's better or worse.

Ok that makes sense, thanks for the adult response.  Do you know what the difference needs to be in these types of studies to be found significant?  Again sincere questions as I have no idea.

[Hards Alumni]

You were wrong and remain wrong.
Maybe for once in your life you should read beyond the headline.

He is the poster child for cognitive bias.

[Boozemon Barro]

https://twitter.com/CaldronPool/status/1495738643180568577?t=jJbftALdkIirVnhE4scqJg&s=19